Lobular Carcinoma In Situ
- Usually incidental finding at biopsy
- Younger premenopausal women
- 1% risk of breast cancer per year
- The future cancer can appear in either breast
- If surgery is to be considered, the procedure of choice is bilateral mastectomy
- Tamoxifen can reduce future risk of breast cancer by 50%
Increased probability of developing a carcinoma of the breast
- This can happen in 20-30 years after diagnosis of LCIS (Lobular carcinoma in situ)
- 1% risk increase of breast cancer per year in someone diagnosed with LCIS
- No role for sentinel lymph node biopsy.
- Treatment for Lobular Carcinoma In Situ (LCIS)
- Close observation
- Consider repeat mammogram in 6 months.
- Informed of increased risk of breast cancer
- No role for re-excision, SLN or irradiation.
- Tamoxifen should be considered with a nearly 50% reduction in cancer formation in women with LCIS
- For patients who insist on a surgical operation – a bilateral total mastectomy would be the procedure of choice because the risk of breast cancer is equal on both sides.