Paget’s Disease of the Breast
- Diagnosis can be confirmed with a punch biopsy the nipple areolar complex.
- Classically present with eczematous changes of the nipple which can progress to bleeding and ulceration.
- More than 90% of patients have underlying carcinoma (in situ or invasive)
- Cancer involving skin and nipple.
- Treatment: mastectomy traditionally. But could be nipple areolar excision with central lumpectomy with radiation therapy (breast conservation therapy) – similar results.
- 50% of patients with Paget’s disease will present with palpable mass.
- May be a role for MRI – deeper breast tissue disease may be missed radiographically and MRI can help detect.
What is breast conservation therapy?
A lesser amount of surgery than mastectomy. Lumpectomy
Paget’s diease of the breast is also known as?
- Paget’s disease of the nipple
- Mammary paget disease