Phyllodes tumors of the breast:
- Not easily distinguished from fibroadenomas on physical exam and even challenging on radiological studies
- Rarely involve the nipple-areolar complex
- Most are in the upper outer quadrant
- Central phyllodes tumors may present with bloody nipple discharge or nipple retraction
- Few have been reported in men
- Primary goal for treatment of phyllodes tumor is to achieve a wide negative margin with a rim of at least 1 cm of uninvolved tissue.
- Total mastectomy may be required for lesions too big to achieve a 1 cm margin without markedly deforming the breast or for repeated local recurrences