{"id":28,"date":"2013-09-15T17:26:39","date_gmt":"2013-09-15T17:26:39","guid":{"rendered":"http:\/\/www.breastguide.com\/breastcancerblog\/?p=28"},"modified":"2013-09-15T17:32:12","modified_gmt":"2013-09-15T17:32:12","slug":"lobular-carcinoma-in-situ-incidental-tamoxifen","status":"publish","type":"post","link":"http:\/\/www.breastguide.com\/breastcancerblog\/lobular-carcinoma-in-situ-incidental-tamoxifen\/","title":{"rendered":"Lobular Carcinoma In Situ, a incidental finding, consider Tamoxifen"},"content":{"rendered":"<h2>Lobular Carcinoma In Situ<\/h2>\n<ul>\n<li>Usually incidental finding at biopsy<\/li>\n<li>Younger premenopausal women<\/li>\n<li>1% risk of breast cancer per year<\/li>\n<li>The future cancer can appear in either breast<\/li>\n<li>If surgery is to be considered, the procedure of choice is bilateral mastectomy<\/li>\n<li>Tamoxifen can reduce future risk of breast cancer by 50%<\/li>\n<\/ul>\n<h3>Increased probability of developing a carcinoma of the breast<\/h3>\n<ul>\n<li>This can happen in 20-30 years after diagnosis of LCIS (Lobular carcinoma in situ)<\/li>\n<li><strong>1% risk increase of breast cancer per year<\/strong> in someone diagnosed with LCIS<\/li>\n<li>No role for <a title=\"Sentinel Lymph Node SLN\" href=\"http:\/\/www.breastguide.com\/breastcancerblog\/sentinel-lymph-node-surgery-for-breast-cancer\/\">sentinel lymph node biopsy<\/a>.<\/li>\n<li>Treatment for Lobular Carcinoma In Situ (LCIS)<\/li>\n<li>Close observation<\/li>\n<li>Consider repeat mammogram in 6 months.<\/li>\n<li>Informed of increased risk of breast cancer<\/li>\n<li>No role for re-excision, SLN or irradiation.<\/li>\n<li><strong>Tamoxifen<\/strong> should be considered with a nearly 50% reduction in cancer formation in women with LCIS<\/li>\n<li>For patients who insist on a surgical operation &#8211; a bilateral total mastectomy would be the procedure of choice because the risk of breast cancer is equal on <strong>both sides<\/strong>.<\/li>\n<\/ul>\n<figure id=\"attachment_31\" aria-describedby=\"caption-attachment-31\" style=\"width: 300px\" class=\"wp-caption alignnone\"><a href=\"http:\/\/www.breastguide.com\/breastcancerblog\/wp-content\/uploads\/2013\/09\/tamoxifen.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-31\" alt=\"Tamoxifen mechanism of action.  Breast Cancer.\" src=\"http:\/\/www.breastguide.com\/breastcancerblog\/wp-content\/uploads\/2013\/09\/tamoxifen-300x202.jpg\" width=\"300\" height=\"202\" \/><\/a><figcaption id=\"caption-attachment-31\" class=\"wp-caption-text\">Tamoxifen mechanism<\/figcaption><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Lobular Carcinoma In Situ Usually incidental finding at biopsy Younger premenopausal women 1% risk of breast cancer per year The future cancer can appear in either breast If surgery is to be considered, the procedure of choice is bilateral mastectomy Tamoxifen can reduce future risk of breast cancer by 50% Increased probability of developing a &hellip; <a href=\"http:\/\/www.breastguide.com\/breastcancerblog\/lobular-carcinoma-in-situ-incidental-tamoxifen\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Lobular Carcinoma In Situ, a incidental finding, consider Tamoxifen<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[58,3,59,57,10,44,60,8],"tags":[61,63,64,62],"class_list":["post-28","post","type-post","status-publish","format-standard","hentry","category-bilateral-mastectomy","category-breast-cancer","category-breast-cancer-drugs","category-lobular-carcinoma-in-situ","category-recurrence","category-sentinel-lymph-node","category-tamoxifen","category-total-mastectomy","tag-bilateral-mastectomy-2","tag-lcis","tag-risk","tag-sln"],"_links":{"self":[{"href":"http:\/\/www.breastguide.com\/breastcancerblog\/wp-json\/wp\/v2\/posts\/28","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.breastguide.com\/breastcancerblog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.breastguide.com\/breastcancerblog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.breastguide.com\/breastcancerblog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.breastguide.com\/breastcancerblog\/wp-json\/wp\/v2\/comments?post=28"}],"version-history":[{"count":4,"href":"http:\/\/www.breastguide.com\/breastcancerblog\/wp-json\/wp\/v2\/posts\/28\/revisions"}],"predecessor-version":[{"id":33,"href":"http:\/\/www.breastguide.com\/breastcancerblog\/wp-json\/wp\/v2\/posts\/28\/revisions\/33"}],"wp:attachment":[{"href":"http:\/\/www.breastguide.com\/breastcancerblog\/wp-json\/wp\/v2\/media?parent=28"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.breastguide.com\/breastcancerblog\/wp-json\/wp\/v2\/categories?post=28"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.breastguide.com\/breastcancerblog\/wp-json\/wp\/v2\/tags?post=28"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}