{"id":26,"date":"2013-09-15T16:01:20","date_gmt":"2013-09-15T16:01:20","guid":{"rendered":"http:\/\/www.breastguide.com\/breastcancerblog\/?p=26"},"modified":"2013-09-15T16:01:20","modified_gmt":"2013-09-15T16:01:20","slug":"advanced-infiltrating-ductal-carcinoma-of-the-breast","status":"publish","type":"post","link":"http:\/\/www.breastguide.com\/breastcancerblog\/advanced-infiltrating-ductal-carcinoma-of-the-breast\/","title":{"rendered":"Advanced Infiltrating Ductal Carcinoma of the Breast"},"content":{"rendered":"<h2>Locally Advanced Breast Cancer<\/h2>\n<p>10-30% of all primary breast cancers are diagnosed as <a title=\"locally advanced\" href=\"http:\/\/www.breastguide.com\/breastcancerblog\/skin-sparing-mastectomy\/\">locally advanced <\/a>which prohibits <a title=\"Breast conservation surgery\" href=\"http:\/\/www.breastguide.com\/breastcancerblog\/pagets-disease-of-the-breast\/\">breast conservation<\/a> methods. \u00a0<a title=\"stage III breast cancer\" href=\"http:\/\/www.breastguide.com\/breastcancerblog\/skin-sparing-mastectomy\/\">Stage III breast cancer<\/a> is considered locally advanced.<\/p>\n<h3>Stage (grade) III Breast Cancer<\/h3>\n<p>An example would be a 6 cm breast mass diagnosed as infiltrating ductal carcinoma with spread to lymph nodes. \u00a0(T3 N1 Mx)<\/p>\n<p>Other examples:<\/p>\n<ul>\n<li>Tumor is larger than 5 cm with positive spread to axillary lymph nodes, but the lymph nodes aren\u2019t attached to each other. \u00a0Stage IIIA.<\/li>\n<li>Tumor is smaller than 5 cm with positive spread of lymph nodes growing into each other and surrounding tissue. \u00a0Stage IIIA.<\/li>\n<li>Tumor is smaller than 5 cm, but the cancer has spread to lymph nodes above the collar bone. \u00a0Stage IIIB.<\/li>\n<li>Inflammatory breast cancer is considered stage IIIB breast cancer.<\/li>\n<\/ul>\n<h3>Treatment of locally advanced breast cancer<\/h3>\n<p>Neoadjuvant therapy is a historical term. \u00a0Now called <strong>primary systemic therapy<\/strong>. \u00a0This is giving chemotherapy prior to operation.<\/p>\n<p>Workup includes bone scan and abdominal CT prior to initiating chemotherapy.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Locally Advanced Breast Cancer 10-30% of all primary breast cancers are diagnosed as locally advanced which prohibits breast conservation methods. \u00a0Stage III breast cancer is considered locally advanced. Stage (grade) III Breast Cancer An example would be a 6 cm breast mass diagnosed as infiltrating ductal carcinoma with spread to lymph nodes. \u00a0(T3 N1 Mx) &hellip; <a href=\"http:\/\/www.breastguide.com\/breastcancerblog\/advanced-infiltrating-ductal-carcinoma-of-the-breast\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Advanced Infiltrating Ductal Carcinoma of the Breast<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[50,51,52],"tags":[54,53,56,55],"class_list":["post-26","post","type-post","status-publish","format-standard","hentry","category-chemotherapy","category-locally-advanced-breast-cancer","category-primary-systemic-therapy","tag-abdominal-ct","tag-bone-scan","tag-primary-systemic-therapy-2","tag-stage-iii"],"_links":{"self":[{"href":"http:\/\/www.breastguide.com\/breastcancerblog\/wp-json\/wp\/v2\/posts\/26","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.breastguide.com\/breastcancerblog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.breastguide.com\/breastcancerblog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.breastguide.com\/breastcancerblog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.breastguide.com\/breastcancerblog\/wp-json\/wp\/v2\/comments?post=26"}],"version-history":[{"count":1,"href":"http:\/\/www.breastguide.com\/breastcancerblog\/wp-json\/wp\/v2\/posts\/26\/revisions"}],"predecessor-version":[{"id":27,"href":"http:\/\/www.breastguide.com\/breastcancerblog\/wp-json\/wp\/v2\/posts\/26\/revisions\/27"}],"wp:attachment":[{"href":"http:\/\/www.breastguide.com\/breastcancerblog\/wp-json\/wp\/v2\/media?parent=26"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.breastguide.com\/breastcancerblog\/wp-json\/wp\/v2\/categories?post=26"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.breastguide.com\/breastcancerblog\/wp-json\/wp\/v2\/tags?post=26"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}